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Job ID: 161367

Postdoctoral Fellow in Cellular and Molecular Immunology
University of Maryland, Baltimore

Date Posted Jun. 29, 2021
Title Postdoctoral Fellow in Cellular and Molecular Immunology
University University of Maryland, Baltimore
Baltimore, MD, United States
Department Center for Vascular and Inflammatory Diseases
Application Deadline Open until filled
Position Start Date Available Immediately
  • Post-Doc
  • Health Sciences - General
    Biomedical Sciences
    Immunology & Infectious Diseases
    Medical Microbiology

This NIH funded laboratory at the University of Maryland, Baltimore (UMB) investigates the molecular and cellular determinants of alloantigen specific tolerance using murine models of cardiac and pancreatic islet transplantation. Specific investigations involve the determination of mechanisms responsible for remodeling of secondary lymphoid organ structure, and how those mechanisms drive T cell migration, differentiation, and fate determination. The molecular focus of the investigations is directed to chemokines, chemokine receptors, cytokines, sphingosine receptors, lymphotoxin, and stromal fibers. Specific cellular elements include regulatory suppressive T cells, effector T cells, vascular and lymphatic endothelial cells, stromal cells, and dendritic cell subsets. Techniques include heavy reliance on in vivo animal models, migration and trafficking assays, real time imaging and advanced microscopy, multicolor flow and sorting, and a variety of molecular techniques for proteins and nucleic acids.

Successful candidates will have at a minimum a recent PhD in immunology or a highly related biomedical field, demonstration of success in publication and presentation, and familiarity or expertise in many of the techniques utilized by the lab.

Recent Publications
Piao W, Xiong Y, Famulski K, Brinkman CC, Li L, Wagner C, Saxena V, Simon T, Bromberg JS. Regulation of T cell afferent lymphatic migration by targeting LTR-mediated non-classical NFB signaling. Nature Comm. 2018, 9:3020. doi: 10.1038/s41467-018-05412-0
Bromberg JS, Hittle L, Xiong Y, Saxena V, Smyth EM, Li L, Zhang T, Wagner C, Fricke WF, Simon T, Brinkman CC, Mongodin EF. Gut microbiota-dependent modulation of innate immunity and lymph node remodeling affects cardiac allograft outcomes. J Clin Invest Insight 2018, doi: 10.1172/jci.insight.121045
Xiong Y, Piao W, Brinkman CC, Li L, Kulinski JM, Olivera A, Cartier A, Hla T, Hippen K, Blazar B, Schwab SR, Bromberg JS. Sphingosine 1-phosphate (S1P) receptors differentially regulate CD4 T cell migration across afferent lymphatic endothelium. Science Immunology 2019, 4:eaav1263. doi: 10.1126/sciimmunol.aav1263
Piao W, Xiong Y, Li L, Saxena V, Smith KD, Hippen KL, Williams KM, Paluskievicz C, Willsonshirkey M, Stains JP, Abdi R, Blazar BR, Bromberg JS. Regulatory T cells condition endothelial cells for enhanced transendothelial migration. Cell Reports 2020, 30:1052-1062.
Lushen L, Willsonshirkey M, Zhang T, Xiong Y, Piao W, Saxena V, Paluskievicz C, Lee Y, Toney N, Cerel BM, Li Q, Simon T, Smith KD, Hippen KL, Blazar BR, Abdi R, Bromberg JS. The lymph node stromal laminin 5 shapes alloimmunity. J Clin Invest, in press.

  • The University of Maryland, Baltimore is an Equal Opportunity, Affirmative Action employer encouraging excellence through diversity. Minorities, women, individuals with disabilities, and protected veterans encouraged to apply.

Please reference in your cover letter when
applying for or inquiring about this job announcement.

Contact Information

  • Dr. Jonathan Bromberg
    Center for Vascular and Inflammatory Diseases
    University of Maryland, Baltimore
    Baltimore, MD 21201
  • 410-328-0008


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