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Job ID: 183574

Postdoctoral Associate
Cornell University


Date Posted Apr. 11, 2022
Title Postdoctoral Associate
University Cornell University
Ithaca, NY, United States
Department Biomedical Engineering
Application Deadline Open until filled
Position Start Date Available immediately
 
 
  • Post-Doc
  • Biomedical Sciences
 
 

We look for a highly motivated postdoctoral fellow. This position will be supported by an NIH R01 grant that starts in July 2022. We study vascular and lymphatic biology, cancer biology, immunology, and regenerative medicine by employing 3D tissue engineering, organs-on-chip, organoids in vitro platforms, molecular biology methods, and in vivo animal models. We encourage open-minded persons from different backgrounds to apply for the position. The potential start date would be July 1, 2022, but it can be adjusted depending on the candidate's preference and the visa process.

Below is the expertise we seek, but it can be flexible based on the candidate's background and interest.

[Immunology]

  • To deepen our understanding of adaptive immunity and lymph node/lymphoid organ biology
  • Purification, adaptation, activation, and FACS characterization of immune cells (dendritic cells, T/B lymphocytes) obtained from animal and human samples.
  • Monitoring immunity in vitro and in vivo.
  • Modeling systemic/local infections in animal models and in vitro models.
  • In vivo imaging (live or fixed samples) of immune cells and lymphoid organs in mice.
  • Expertise in cancer immunology, lymph nodes, and lymphoid organs is a plus.

[Vascular Biology]

  • To deepen the understanding of blood and lymphatic vascular morphogenesis, homeostasis, and pathogenesis.
  • Purification, maintaining, and culturing of human blood/lymphatic vascular endothelial cells and vascular mural cells (pericytes, smooth muscle cells, etc.) using animal and human samples.
  • Monitoring vascular morphology and function in vitro and in vivo.
  • Monitoring tumor/immune cell interactions to vasculatures in vitro and in vivo.
  • Expertise in vivo implantation of engineered tissues is a plus.
  • Expertise in vascular disease animal models in vivo (lymphedema, hypertension, vascular leakage, etc.) is a plus.

[Cancer Biology]

  • To deepen our understanding of tumor initiation, progression, and interactions with blood and lymphatic vascular structures
  • Knowledge of the mechanobiology of epithelial tumor cells is a plus
  • Monitoring tumor interactions to vasculature in vitro and in vivo.
  • Tumor immunotherapy, tumor metabolism, tumor metastasis, resistance.

[Microfluidics]

  • Designing, fabrication (soft lithography), and characterization of microfluidic devices, lab-on-chip, organ-on-chip, 3D cellularity, tissue level in vitro modeling
  • Cell seeding, cell culturing & maintaining on-chip; and investigating cell mechanics, cell-cell interactions, cell secretome, cell morphology on-chip
  • Experience in developing tissue-level 3D mono/multi-cellular structure in vitro is a plus.
  • Experience in organoids, stem cells, multicellular behaviors, and cells in shear stress is a plus.

[Organoid]

  • To apply the organoid technologies to host immunity, vascular, lymphatic, cancer, and organ regenerative medicine
  • iPSCs differentiation to specific cell types (e.g., liver, gut, brain, heart, endothelial cells, pericytes, etc.).
  • Monitoring and characterizing organoid development in vitro and in vivo.

[Molecular Biology]

  • To deepen our mechanistic understanding of our findings.
  • Knowledge and experience in cloning and genetic engineering in mammalian cells to generate knock-out or knock-in cells (e.g., CRISPR-cas9), and to visualize (e.g., GFP, RFP) specific proteins in the cells for live observation of the proteins.
  • Experience in vascular, immune, and cancer biology is a plus. 

How to apply:
Send your cover letter and current CV that includes your degree information, publications, and the list of 3 references to Dr. Lee.


 
Please reference AcademicKeys.com in your cover letter when
applying for or inquiring about this job announcement.
 
 

Contact Information

 
  • Esak Lee
    Biomedical Engineering
    Cornell University
    Ithaca, NY 14853
  •  
  • el767@cornell.edu

 

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