The extensive complexity of tissue development and maintenance elicits questions about how the genome encodes for the great cellular diversity and morphological flexibility required for healthy function. microRNAs (miRNAs), a class of small non-coding RNAs have emerged as key regulators of gene expression, but their biological functions remain largely unexplored.
The goal of my research is to elucidate the function of miRNAs in development, and to understand their contribution to certain human disease conditions. My lab does this through a multi-disciplinary experimental platform using versatile transgenic technologies, genome engineering techniques, molecular biology, bioinformatics, fluorescence imaging, and optogenetics.
