The central focus of Dr. Stout’s research program is to understand how metabolic disturbances such as obesity, dyslipidemia, and diabetes can promote the aging process and the onset of multimorbidity. He is particularly interested in the role that sex hormones play in regulating these processes due to gender-specific disparities in metabolic disease, inflammatory disorders, and healthspan across the life-cycle. The long-term goal of Dr. Stout laboratory is to develop therapeutic strategies that target metabolic signaling pathways in a manner similar to calorie restriction, thereby diminishing age-related diseases and compressing the period of morbidity in mid-to-late life.
