1) address the challenges of using patient reported outcomes (e.g. health-related quality of life, self-efficacy) in chronic disease management programs, and the use of advanced psychometric approaches for improving the precision and efficiency of outcome evaluations, 2) develop and evaluate the impact of chronic disease computer-enabled self-management interventions integrated into electronic personal health records (e.g. web-based asthma and COPD self-management applications), and 3) knowledge exchange and transfer related to best practices for chronic disease management.