Synergistic Activities I have been associated with the Toxics Use Reduction Institute since its inception, first as Deputy Director and now as Director. In this role, I have facilitated interdisciplinary research toward the goal of reducing the use of toxic chemicals by industry. The Institute has funded research projects in all of the engineering departments at UMass Lowell, including projects performed by the co-PIs on this proposal. In addition, the Institute has worked with scientists and engineers located at institutions throughout the United States and in many other countries to further the goal of reducing the use of toxic chemicals. In recognition of the innovative work performed by the Institute and its partner agencies, the Massachusetts Toxics Use Reduction Program was selected as one of the top ten Innovations in American Government by the Ford Foundation, Harvard University's Kennedy School of Government, and the Council for Excellence in Government in 1999.